![Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets](https://www.mdpi.com/cells/cells-07-00176/article_deploy/html/images/cells-07-00176-g001-550.jpg)
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
![NIK protein production increased in malignant breast cancer tissue. A... | Download Scientific Diagram NIK protein production increased in malignant breast cancer tissue. A... | Download Scientific Diagram](https://www.researchgate.net/publication/369745355/figure/fig5/AS:11431281136213310@1680516896662/NIK-protein-production-increased-in-malignant-breast-cancer-tissue-A-Representative-IHC.png)
NIK protein production increased in malignant breast cancer tissue. A... | Download Scientific Diagram
![NIK protein degradation induced by GA is largely mediated by autophagy.... | Download Scientific Diagram NIK protein degradation induced by GA is largely mediated by autophagy.... | Download Scientific Diagram](https://www.researchgate.net/profile/Guoliang-Qing-2/publication/6272778/figure/fig5/AS:279045934731315@1443541143673/NIK-protein-degradation-induced-by-GA-is-largely-mediated-by-autophagy-A-AICAR-an.png)
NIK protein degradation induced by GA is largely mediated by autophagy.... | Download Scientific Diagram
![Expression levels of NIK protein are correlated with those of its mRNA... | Download Scientific Diagram Expression levels of NIK protein are correlated with those of its mRNA... | Download Scientific Diagram](https://www.researchgate.net/publication/26708904/figure/fig3/AS:667619774443535@1536184366499/Expression-levels-of-NIK-protein-are-correlated-with-those-of-its-mRNA-in-various.png)
Expression levels of NIK protein are correlated with those of its mRNA... | Download Scientific Diagram
![Hsp90 function is required for the increase of NIK protein mediated by... | Download Scientific Diagram Hsp90 function is required for the increase of NIK protein mediated by... | Download Scientific Diagram](https://www.researchgate.net/publication/6272778/figure/fig4/AS:279045934731289@1443541143433/Hsp90-function-is-required-for-the-increase-of-NIK-protein-mediated-by-the-proteasome.png)
Hsp90 function is required for the increase of NIK protein mediated by... | Download Scientific Diagram
![NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-017-02672-0/MediaObjects/41467_2017_2672_Fig1_HTML.jpg)
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
![Non-canonical NF-B stimuli rescue NIK proteins from proteasome-mediated... | Download Scientific Diagram Non-canonical NF-B stimuli rescue NIK proteins from proteasome-mediated... | Download Scientific Diagram](https://www.researchgate.net/publication/7542110/figure/fig4/AS:458982520299523@1486441368447/Non-canonical-NF-B-stimuli-rescue-NIK-proteins-from-proteasome-mediated-degradation-but.png)
Non-canonical NF-B stimuli rescue NIK proteins from proteasome-mediated... | Download Scientific Diagram
![NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes | Cell Death & Disease NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes | Cell Death & Disease](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41419-022-04931-5/MediaObjects/41419_2022_4931_Fig1_HTML.png)
NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes | Cell Death & Disease
NIK protein level and activity are controlled by a negative feedback... | Download Scientific Diagram
![NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcddis.2014.584/MediaObjects/41419_2015_Article_BFcddis2014584_Fig9_HTML.jpg)
NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways | Cell Death & Disease
![Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation | Cell Research Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation | Cell Research](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcr.2007.47/MediaObjects/41422_2007_Article_BFcr200747_Fig6_HTML.jpg)